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Axial Spondyloarthritis
The classic clinical description of ankylosing spondylitis was made in the late 1800s and was refined by the addition of radiographic descriptions during the 1930s. Pathological investigation revealed...
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Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit
Ms. G is a 42-year-old woman admitted to your ICU with septic shock in the setting of a urinary tract infection. She was started on a norepinephrine infusion in the emergency room. Her labs reveal a...
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Polycystic Ovary Syndrome
The polycystic ovary syndrome is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. The polycystic ovary syndrome increases the risk of infertility,...
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A Bruising Loss
Whereas inherited clotting-factor deficiencies are typically clinically evident from birth, the sudden appearance of a bleeding diathesis in a previously healthy adult is suggestive of an acquired...
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Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting
Patients are fearful of nausea and vomiting during the course of cancer treatment, as it is an expected side effect of chemotherapy. Senior oncology physicians describe the early days of cancer...
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A Man in an Unresponsive State
Clinical care for patients with acute liver failure should focus on preventing and treating associated complications, identifying the cause so that targeted therapy (if available) can be initiated, and...
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Initiation Strategies for Renal-Replacement Therapy
Renal-replacement therapy is the cornerstone of the management of severe acute kidney injury. Gaudry et al. compared a strategy of early initiation of renal-replacement therapy with a strategy of...
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27 Overnight Shifts: Lessons Learned from Indian Health Service Providers
At GIMC with my colleague Dr. Adaira Chou The morning after I arrived in New Mexico was beautiful and warm, a pleasant change from the Northeast winter. I was entering my second year of emergency...
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Take the Case Challenge: A Man with Acute Liver Injury
Click to enlarge A 50-year-old man was admitted to the hospital because of increased levels of aminotransferases, hyperbilirubinemia, anemia, and acute kidney injury. What is the most likely...
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Revitalized NEJM.org Offers Something for Every Medical Learner
Lifestyles of medical professionals have changed greatly over the past two decades. Imperatives for pursuing lifelong medical learning have continued to multiply, while time available for doing so has...
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